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Hydrodissection, Anyone? A Patient's Journey From Italy to CT

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Hydrodissection, Anyone? A Patient's Journey From Italy to CT
Written and Medically Reviewed by Dr. Paul Tortland, DO, FAOASM, CAQSM, RMSK, Dual-Board Certified in Sports Medicine & Regenerative Medicine
·
October 18, 2026
What You Need to Know

Nerve hydrodissection uses image-guided injections to separate an irritated or entrapped nerve from surrounding tissue, and is sometimes used in complex, previously-treated cases of thoracic outlet syndrome. In this case, it's being used alongside scar tissue injection for a patient whose TOS symptoms persisted after multiple prior surgeries, including first rib resection.

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Direct Answer: Nerve hydrodissection uses image-guided injections to separate an irritated or entrapped nerve from surrounding scar tissue and adjacent structures. It's sometimes used in complex, previously-treated cases of thoracic outlet syndrome (TOS) when symptoms persist despite prior surgery — as in the case below, where it's being used alongside injection of surgical scar tissue itself.

A Patient's Journey From Italy

A woman in her 30s recently traveled from Bologna, Italy specifically to see Dr. Tortland for hydrodissection treatment. She is being treated for bilateral brachial plexus hydrodissection — both supraclavicular and infraclavicular — for thoracic outlet syndrome that had failed multiple prior surgeries, including a first rib resection.

Thoracic outlet syndrome is frequently misdiagnosed, and Dr. Tortland has seen a number of patients who were not well served by surgery for it, particularly spinal surgery performed for symptoms that were ultimately not spinal in origin. Because of this, he is highly selective about his surgical referral network, trusting only a small number of spine surgeons with his patients — the standard being surgeons he would trust to treat his own family. Like many patients he sees, this patient had consulted numerous physicians without relief before her evaluation.

As part of her treatment, her surgical scars were also injected — a common source of ongoing pain and restricted movement after surgery, seen frequently after total knee replacement, shoulder surgery, and even C-sections.

She had her first treatment earlier this week and is already reporting improvement. She returns for a second round of treatment before flying back to Italy.

What Is Nerve Hydrodissection?

Hydrodissection is an ultrasound-guided injection technique that separates a peripheral nerve from surrounding tissue when compression, tethering, or scarring is contributing to a patient's symptoms. It typically uses dextrose in sterile water, sometimes combined with PRP, injected precisely around the nerve under real-time ultrasound guidance. A 2025 clinical review in Muscle & Nerve notes that hydrodissection can play a role specifically in post-surgical nerve entrapment, including cases where scar tissue from a prior procedure contributes to ongoing nerve symptoms.

Thoracic Outlet Syndrome: An Often-Missed Diagnosis

Thoracic outlet syndrome refers to compression of the nerves, arteries, or veins passing between the collarbone and first rib. Symptoms — arm pain, numbness, tingling, weakness, or a sense of heaviness — can mimic cervical spine disease, which is a common source of misdiagnosis and, at times, unnecessary spinal intervention. A 2022 review in Deutsches Ärzteblatt International notes that neurogenic TOS studies remain limited in number and quality, and that surgical approach varies by surgeon experience and anatomy — underscoring why an accurate diagnosis, including a careful physical exam and appropriate imaging, is essential before any treatment, surgical or non-surgical, is considered. Recently published case reports have also described ultrasound-guided hydrodissection as a treatment option in select, refractory neurogenic TOS cases, including those involving a cervical rib or subclavius muscle involvement.

Treating Surgical Scar Tissue

Scar tissue from prior surgery can itself become a source of pain, restricted motion, or nerve irritation. Injecting scar tissue directly — sometimes combined with hydrodissection of adjacent nerves — is a treatment option in appropriately selected patients with a clear scar-related contribution to their symptoms.

Limitations — What This Does Not Do

A single patient's experience, including this one, is not a guarantee of outcome for any other patient — individual results vary considerably, particularly in complex, multiply-operated cases like thoracic outlet syndrome. Hydrodissection is not a cure for TOS, does not reverse prior surgical changes, and is not appropriate for every patient with TOS symptoms. It is not a substitute for an accurate diagnosis, and in some patients — a 2019 outcomes study in the Journal of Vascular Surgery found roughly 60% of a large neurogenic TOS cohort ultimately required surgery after physical therapy alone was insufficient — surgery remains the more appropriate option. Candidacy depends on a thorough, individualized evaluation.

Dr. Tortland's Perspective

Cases like this are a reminder of how often thoracic outlet syndrome is misunderstood, and how much unnecessary surgery can follow from an incorrect diagnosis. I'm careful about who I refer patients to for spinal surgery — only surgeons I would trust with my own family — and I try to give patients who have already been through multiple procedures an honest, thorough re-evaluation rather than another quick answer.

Comparison at a Glance

TreatmentMechanismDurationBest Candidate Stage
Nerve hydrodissectionImage-guided fluid injection separates an irritated or entrapped nerve from surrounding tissue and scarVariable; repeat treatment may be neededSelected patients with nerve entrapment, tethering, or post-surgical scar-related symptoms
Scar-tissue injectionInjects symptomatic surgical scar tissue directly to reduce restriction or irritationVariable; depends on the underlying scar-related problemPatients with a documented scar-related contribution to pain or restricted motion
Physical therapy / conservative careProgressive rehabilitation addresses movement, strength, and functional contributorsUsually weeks to monthsInitial management or patients who may improve without an injection
Surgical treatmentCorrects selected structural causes of thoracic outlet or nerve compressionLong-term structural treatment; recovery variesPatients with a confirmed structural problem who do not respond adequately to conservative care

Frequently Asked Questions

What is nerve hydrodissection used for?

It's used when a nerve is compressed, tethered, or irritated by surrounding tissue or scarring, including select cases of thoracic outlet syndrome and post-surgical nerve entrapment.

Can hydrodissection help after failed surgery for thoracic outlet syndrome?

It may be considered in select patients whose symptoms persist after surgery, though outcomes vary and candidacy depends on an individualized evaluation.

Is injecting surgical scar tissue a common treatment?

Scar tissue injection is used when scarring from a prior surgery — such as total knee replacement, shoulder surgery, or C-section — is contributing to ongoing pain or restricted motion.

Does nerve hydrodissection hurt during the injection?

Most patients feel pressure and brief stinging from the needle and fluid rather than sharp pain, since the injection is done under ultrasound guidance with local anesthetic. Some temporary soreness at the injection site afterward is common.

How long does relief from hydrodissection typically last?

Duration varies by patient and the specific nerve or scar tissue involved. Some patients get lasting relief from one treatment, while others need a repeat session or ongoing management as part of a broader care plan.

How many hydrodissection treatments will I need?

This varies by diagnosis and response to the first treatment. Some patients improve significantly after one session; others benefit from a short series spaced weeks apart.

Is nerve hydrodissection covered by insurance?

Coverage varies by diagnosis, payer, and whether the nerve entrapment is clearly documented. It's worth confirming your specific coverage and costs before scheduling.

How is hydrodissection different from a cortisone injection or nerve block?

A cortisone injection reduces inflammation and a diagnostic nerve block temporarily numbs a nerve to confirm it as the pain source; hydrodissection uses fluid to mechanically separate a nerve from surrounding tissue that may be compressing or tethering it, which is a different mechanism aimed at the entrapment itself.

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Dual-Board-Certified · Fellowship-Trained · Specialist in Regenerative Orthopedics

About Paul D. Tortland, DO

Dr. Paul Tortland was the first physician in southern New England to offer PRP and BMA + MFAT stem cell treatments for Orthopedic injuries, treating patients since 2007 with a customized, ultrasound-guided approach and measured, high-concentration PRP preparations at his Glastonbury, CT practice.

References & Further Reading

View 5 medical references and further reading
  • Yoon Y, et al. "Ultrasound-Guided Hydrodissection for Neurogenic Thoracic Outlet Syndrome Caused by a Cervical Rib: A Case Report." Cureus. 2026. https://doi.org/10.7759/cureus.104595
  • Yoon Y, et al. "Ultrasound-Guided Hydrodissection of the Subclavius Muscle Region in Neurogenic Thoracic Outlet Syndrome: A Case Report." Frontiers in Medicine. 2026. https://doi.org/10.3389/fmed.2026.1804081
  • Dengler NF, et al. "Neurogenic Thoracic Outlet Syndrome—Presentation, Diagnosis, and Treatment." Deutsches Ärzteblatt International. 2022. https://doi.org/10.3238/arztebl.m2022.0296
  • Balderman J, et al. "Physical Therapy Management, Surgical Treatment, and Patient-Reported Outcomes Measures in a Prospective Observational Cohort of Patients With Neurogenic Thoracic Outlet Syndrome." Journal of Vascular Surgery. 2019. https://doi.org/10.1016/j.jvs.2018.12.027
  • Colorado B, McNeill D, Norbury J. "Ultrasound-Guided Nerve Hydrodissection for Peripheral Entrapment Neuropathies." Muscle & Nerve. 2025. https://doi.org/10.1002/mus.28471

Learn more on this site: Nerve hydrodissection