The Full Answer
PRP does not work like a cortisone shot, which can bring rapid but temporary relief by suppressing inflammation. PRP instead relies on stimulating the body's own repair process, which takes time to build. A short window of increased soreness in the first three to seven days is a normal part of that process, not a sign the treatment isn't working. Patients who are going to respond typically start noticing a difference within a matter of weeks, with results continuing to build for a couple of months, consistent with the six-to-twelve-month benefit window seen in patients who do respond.
What the Current Evidence Shows
Who May Benefit
When Surgery May Be More Appropriate
Dr. Tortland's Perspective
Setting expectations up front — that PRP is a slower, biologic process rather than an immediate fix — helps patients avoid concluding too early that a treatment 'didn't work' when they're still in the normal early window.