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Do Corticosteroid Injections Damage the Tendon in Tennis Elbow? What a New MRI Study Shows

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Dr. Paul Tortland, DO, Dual-Board Certified in Sports Medicine & Regenerative Medicine
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Do Corticosteroid Injections Damage the Tendon in Tennis Elbow? What a New MRI Study Shows
Written and Medically Reviewed by Dr. Paul Tortland, DO, FAOASM, CAQSM, RMSK, Dual-Board Certified in Sports Medicine & Regenerative Medicine
·
October 18, 2026
What You Need to Know

A 2026 retrospective, multicenter MRI study of 147 patients with chronic lateral epicondylitis found that those who had received a prior corticosteroid injection had significantly more severe common extensor tendon damage (adjusted OR 2.78) and larger tendon lesions than those who had not — imaging-based evidence that corticosteroid injections may be associated with structural tendon harm rather than healing in tennis elbow.

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Cortisone - Band-aid or lasting damage?

A question I get often from patients with tennis elbow: does a cortisone shot actually hurt the tendon in the long run? A newly published MRI study gives us some of the clearest evidence yet, and the answer leans toward yes.

What the study looked at

In a retrospective, multicenter cross-sectional study published in BMC Musculoskeletal Disorders, researchers reviewed elbow MRIs from 147 patients with clinically diagnosed lateral epicondylitis (LE), all with symptoms lasting six months or longer, imaged between 2015 and 2023. Of those patients, 63 (42.9%) had received at least one prior corticosteroid (glucocorticoid) injection at the common extensor origin before their MRI.

Tendon damage was graded using the Walz classification, an MRI-based staging system radiologists and orthopedists use to score the severity of common extensor tendon pathology in lateral epicondylitis, ranging from Grade 0 (normal) to Grade 3 (severe or complete tear). The researchers also measured lesion size directly on MRI, and adjusted their analysis for age, sex, occupational workload, treatment center, and symptom duration.

What the researchers found

The authors were careful to note that because this was a retrospective, cross-sectional design, it can only show an association between corticosteroid injection and tendon damage, not prove that the injections caused it — patients with more severe disease may simply be more likely to have been offered an injection in the first place. Still, this adds meaningful imaging-based evidence to a growing body of literature raising concern about the effects of local corticosteroid use on tendon structure.

My take: dose matters, and so do the alternatives

I've argued for years that most patients don't need a high dose of steroid to get the clinical result they're after. That's not just clinical opinion — a 2023 randomized, controlled, double-blind study found that 10 mg of triamcinolone was non-inferior to 40 mg for treating knee osteoarthritis, meaning the lower dose worked just as well with presumably less tissue exposure to steroid (Utamawatin K, et al. BMC Musculoskeletal Disorders. 2023;24:92).

If a corticosteroid injection is going to be used at all, using the lowest effective dose is a reasonable way to help modulate some of its potential downsides.

But the bigger picture here is that we now have a widening set of treatment options for lateral epicondylitis that are actually designed to promote tendon healing rather than simply suppress inflammation, including physical therapy, PRP (platelet-rich plasma), Tenex/TenJet percutaneous tenotomy, and energy-based modalities like EMTT, ESWT, and laser therapy. For most patients with chronic tennis elbow, I believe these regenerative and healing-focused options deserve serious consideration before reaching for a cortisone shot. In our practice, we often see patients who got good short-term relief from a cortisone shot for tennis elbow, only to come back months later with the same pain and a tendon that looks worse on imaging — which is exactly the pattern this kind of research is trying to explain.

Bottom line

This study doesn't prove that corticosteroid injections cause tendon damage in tennis elbow, but it does add meaningful imaging-based weight to the argument that CSI may come with a real structural cost. Patients and clinicians should weigh that risk against the short-term symptom relief CSI provides, and consider whether a healing-oriented alternative might be the better first move.

Source: Henze AS, Eckl L, Kadantsev P, Ambacher T, Kuehn P, Schoch C, Siebenlist S, Geyer S. MRI severity of common extensor origin damage associated with prior glucocorticoid injection in chronic lateral epicondylitis: a retrospective multicenter analysis. BMC Musculoskeletal Disorders. 2026. https://doi.org/10.1186/s12891-026-10450-7

Limitations: What This Research Does Not Mean

This research does not mean corticosteroid injections are never appropriate — they can still have a role in short-term pain relief for select patients and specific situations. What the evidence supports is caution about repeated or first-line steroid use for tendon problems like tennis elbow, not a blanket condemnation. Alternatives such as PRP are not risk-free either and do not work for every patient; the right choice depends on the specific diagnosis, tendon appearance on ultrasound, and how long symptoms have been present.

Dr. Tortland's Perspective

Dr. Tortland has been building non-surgical treatment pathways for tendon injuries since founding his practice in 1995, when prolotherapy was his primary regenerative tool; PRP and other orthobiologic options followed over the next decade and a half. "Every time a patient tells me a cortisone shot worked great for a few weeks and then stopped working, I hear the same story," he says. "The tendon didn't get better during that relief window — it just got quiet for a while. My approach is to confirm the diagnosis with ultrasound first, understand how damaged the tendon actually is, and then choose a treatment that's trying to heal the tissue, not just mute the pain signal for a few weeks."

Comparison at a Glance

TreatmentMechanismDurationBest Candidate Stage
Corticosteroid injectionReduces inflammation and pain signaling around the affected tendonOften short-term symptom relief; duration variesSelected patients needing symptom control, with tendon risks considered
Conservative rehabilitationProgressive loading and strengthening improve tendon capacity and functionUsually weeks to monthsFirst-line management for most tennis elbow presentations
PRP (platelet-rich plasma)Concentrated autologous platelets provide signaling factors intended to influence the tendon healing environmentImprovement develops over weeks to monthsPersistent tendinopathy or symptoms despite an appropriate rehabilitation trial
Surgical treatmentRepairs or removes severely damaged tendon tissue when indicatedLong-term structural treatment; rehabilitation takes monthsSelected refractory cases with substantial structural disease after non-surgical care

Frequently Asked Questions

If corticosteroid injections can damage the tendon, what's a safer option for tennis elbow?

Most cases of tennis elbow (lateral epicondylitis) improve with activity modification and targeted rehabilitation exercises first. For persistent symptoms, PRP is generally considered a more tendon-friendly injection option than corticosteroid, since it's intended to support tendon healing rather than suppress inflammation at the tendon itself.

Should I stop a corticosteroid injection I already had from working?

A single prior corticosteroid injection doesn't necessarily mean lasting damage in every patient — this study found an association across a group of patients with chronic symptoms, not a guaranteed outcome for any one individual. If you're concerned, this is worth discussing directly with your physician.

How is tendon damage from corticosteroid actually diagnosed?

MRI is the primary tool for evaluating tendon structure and damage in cases like this, since it can show changes in tendon thickness, tearing, and signal characteristics that aren't visible on physical exam alone.

Does this mean corticosteroid injections should never be used for tendon pain?

Not necessarily in every situation, but this evidence adds to a broader pattern of research questioning corticosteroid's role specifically in tendon conditions (as opposed to joint or bursa conditions), where its anti-inflammatory effect may come at the cost of tissue quality over time.

I already got a cortisone shot for my tennis elbow months ago — did I damage my tendon permanently?

Not necessarily. This study found an association between prior injection and more severe tendon findings on MRI, not proof that any one injection causes permanent, irreversible damage. If you're still having symptoms, a current ultrasound evaluation is a more useful next step than worrying retroactively about a past injection.

Does this study mean I should never get a cortisone shot again?

No. The research raises a caution about repeated or first-line steroid use in tendon problems specifically, not a blanket rule against corticosteroid injections, which still have a legitimate role for appropriately selected patients and situations.

What's the difference between how corticosteroid and PRP affect a tendon?

Corticosteroid primarily suppresses inflammation and can provide fast symptom relief, while PRP is intended to support the tendon's own healing and remodeling process. This study's concern is specifically about structural tendon changes associated with corticosteroid, not with PRP.

How many corticosteroid injections for tennis elbow is considered too many?

This particular study found that even a single prior injection was associated with worse tendon findings — the number of injections wasn't what predicted severity. That's a reason to be selective about using corticosteroid at all for tendon pain, not just about limiting how many times it's repeated.

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About Paul D. Tortland, DO

Dr. Paul Tortland was the first physician in southern New England to offer PRP and BMAC + MFAT stem cell treatments for Orthopedic injuries, treating patients since 2007 with a customized, ultrasound-guided approach and measured, high-concentration PRP preparations at his Glastonbury, CT practice.

References & Further Reading

View 2 medical references and further reading
  • Henze AS, Eckl L, Kadantsev P, Ambacher T, Kuehn P, Schoch C, Siebenlist S, Geyer S. "MRI severity of common extensor origin damage associated with prior glucocorticoid injection in chronic lateral epicondylitis: a retrospective multicenter analysis." BMC Musculoskeletal Disorders. 2026. https://doi.org/10.1186/s12891-026-10450-7
  • Utamawatin K, et al. "Randomized, controlled, double-blind study: 10 mg vs. 40 mg triamcinolone for knee osteoarthritis." BMC Musculoskeletal Disorders. 2023;24:92.

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